Key papers:

  • Kroeze Y, Oti M, van Beusekom E, Cooijmans RH, van Bokhoven H, Kolk SM, Homberg JR, Zhou H (2017). Transcriptome Analysis Identifies Multifaceted Regulatory Mechanisms Dictating a Genetic Switch from Neuronal Network Establishment to Maintenance During Postnatal Prefrontal Cortex Development. Cerebral Cortex Jan 19
  • Witteveen JS, Willemsen MH, Dombroski TCD, van Bakel NHM, Nillesen WM, van Hulten JA, Jansen EJR, Verkaik, D, Veenstra-Knol HE, van Ravenswaaij-Arts CMA van, Klein Wassink-Ruiter JS, Vincent M, David A, Le Caignec C, Schieving J, Gilissen C, Foulds N, Rump P, Strom T, Cremer K, Zink AM, Engels H, de Munnik SA, Visser, JE, Brunner HG, Martens, GJM, Pfundt R, Kleefstra T, Kolk SM (2016). Haploinsufficiency of MECP2-interacting transcriptional co-repressor SIN3Acauses mild intellectual disability by affecting the development of cortical integrity. Nature Genetics, 48(8):877-87.


  • Kos A, Klein-Gunnewiek T, Meinhardt J, Loohuis NF, van Bokhoven H, Kaplan BB, Martens GJ, Kolk SM, Aschrafi A. (2016). MicroRNA-338 Attenuates Cortical Neuronal Outgrowth by Modulating the Expression of Axon Guidance Genes. Molecular Neurobiology 14 May .
  • Schubert D, Martens GJM and Kolk SM (2014). Molecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disorders. Molecular Psychiatry Dec 2. doi: 10.1038/mp.2014.147.

    SchubertMartensKolk_Mol Psych_2014.pdf

    Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lilleväli K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ. (2014) Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron 83(2):372-87. doi: 10.1016/j.neuron.2014.05.036.

    Schmidt et al Neuron 2014.pdf

  • Homberg JR, Kolk SM and Schubert D (2013) Editorial perspective of the Research Topic “Deciphering serotonin's role in neurodevelopment.” Frontiers in Cellular Neuroscience 7:212. doi: 10.3389/fncel.2013.00212 
  • Witteveen J.S., Middelman A., van Hulten S., Martens G.J.M., Homberg J.R., Kolk S.M. The neurodevelopmental role of serotonin in guiding rostral raphe-derived projections towards mPFC. (2013). Frontiers in Cellular Neuroscience 7(143):1-16. 


  • Kinast K., Peeters D., Schubert D., Kolk S.M., Homberg J.R. (2013). Genetic and pharmacological manipulations of the serotonergic system in early life: Neurodevelopmental underpinnings of autism-related behaviour. Frontiers in Cellular Neuroscience 7 (72):1-17.
  • Kos A., Olde Loohuis N.F., Wieczorek M.L., Glennon J.C., Martens G.J., Kolk S.M., Aschrafi A. (2012). A potential regulatory role for intronic microRNA-338-3p for its host gene encoding Apoptosis-associated Tyrosine Kinase. PLoS One 7(2):e31022.
  • Kan AA, van der Hel WS, Kolk SM, Bos IW, Verlinde SA, van Nieuwenhuizen O, de Graan PN. (2012). Prolonged increase in rat hippocampal chemokine signalling after status epilepticus. J Neuroimmunol. 245(1-2):15-22.
  • Kolk S.M., de Mooij-Malsen A.J., Martens G.J.M. (2011). Spatiotemporal molecular approach of in utero electroporation to functionally decipher endophenotypes in neurodevelopmental disorders. Frontiers in Molecular Neuroscience 4:37:1-7.
  • Kolk, S.M., Gunput, R.F., Tran, T.S., van den Heuvel, D.M.A., Prasad, A.A., Hellemons, J.C.G.M., Adolfs, Y., Ginty, D.D., Kolodkin, A.L., Burbach, J.P.H., Smidt, M.P., Pasterkamp, R.J. (2009). Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting. Journal of Neuroscience 29:12542-12557.
  • North, H.A, Kolk, S.M, Zhao, X, Clifford, M. A., and Donoghue, M.J. (2009). Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling. Development 136(14):2467-76.