Welcome to the Kolk Lab!
Molecular framework underlying developing brain areas
Our developing brain is a remarkable triumph of evolution. Every neurodevelopmental step needs to be meticulously coordinated by a plethora of molecules in a timely fashion in order to generate specific brain areas dedicated to a particular function. Genetic mutations or environmental influences, such as certain medications or viral infections, can perturb these neurodevelopmental steps.
Our team focuses on cellular and molecular mechanisms of developing brain areas and how genetic and environmental influence key developmental steps. Using a variety of functional assays in various models, we aim to unravel the molecular framework of developing neural circuits, especially those involved in neurodevelopmental disorders.